Scientists identify new fuel-delivery route for cells

Scientists identify new fuel-delivery route for cells

Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it.

Past work has shown that NAD levels in tissues throughout the body decrease with age. One way cells manufacture NAD begins with a precursor molecule called nicotinamide mononucleotide (NMN), which is found naturally in foods such as edamame, broccoli, cabbage, cucumber, and avocado. But how NMN gets into cells to be processed into NAD has long been a mystery.

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